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ORBITAL SOCIETY



Eyelid Oncology

Eyelid Lumps and Bumps - could it be cancer?

This information is not meant to replace the advice of your physician and is not to be considered medical advice, diagnosis or treatment. Should you have any concern please contact your physician directly. Read our disclaimer

Basal Cell Carcinoma

Basal Cell Carcinoma, Dr. Kimberly Cockerham

Basal Cell Carcinoma

Eyelid Cancer or Non-Cancerous Cancerous

Infiltrative Basal Cell Carcinoma

Infiltrative Basal Cell Carcinoma

Eyelid Cancer or Non-Cancerous Cancerous

Medial Canthal Basal Cell Carcinoma

Medial Canthal Basal Cell Carcinoma

Eyelid Cancer or Non-Cancerous Cancerous

Ulcerative Basal Cell Carcinoma , Dr. Cockerham

Ulcerative Basal Cell Carcinoma

Eyelid Cancer or Non-Cancerous Cancerous

Umbilicated Basal Cell Carcinoma

Umbilicated Basal Cell Carcinoma

Eyelid Cancer or Non-Cancerous Cancerous

Non-pigmented Mole vs. Basal Cell Carcinoma at Caleyes.com

Non-pigmented Mole vs. Basal Cell Carcinoma

Eyelid Cancer or Non-Cancerous Cancerous

Squamous Cell Carcinoma

Cystic Squamous Cell Carcinoma

Cystic Squamous Cell Carcinoma

Eyelid Cancer or Non-Cancerous Cancerous

Squamous Cell Carcinoma of the eye, Los Altos California

Squamous Cell Carcinoma

Eyelid Cancer or Non-Cancerous Cancerous

Eyelid Melanoma

Melanoma

Melanoma

Eyelid Cancer or Non-Cancerous Cancerous

Sebaceous Cell Carcinoma

Sebaceous Cell Carcinoma at Caleyes.com

Sebaceous Cell Carcinoma

Eyelid Cancer or Non-Cancerous Cancerous

Sebaceous Cell Carcinoma

Sebaceous Cell Carcinoma

Eyelid Cancer or Non-Cancerous Cancerous

This information is not meant to replace the advice of your physician and is not to be considered medical advice, diagnosis or treatment. Should you have any concern please contact your physician directly. Read our disclaimer

Unusual Lesions

Keratoacanthoma

Keratoacanthoma, Dr. Cockerham in California

Keratoacanthoma

Eyelid Cancer or Non-Cancerous Unusual Lesions

Lentigo Maligna

Lentigo Maligna

Lentigo Maligna

Eyelid Cancer or Non-CancerousUnusual Lesions

This information is not meant to replace the advice of your physician and is not to be considered medical advice, diagnosis or treatment. Should you have any concern please contact your physician directly. Read our disclaimer

Non-Cancerous

Hemangioma

Capillary Hemangioma Dr. Kimberly Cockerham

Capillary Hemangioma

Eyelid Cancer or Non-Cancerous Non-Cancerous

Cavernous Hemangioma

Cavernous Hemangioma

Eyelid Cancer or Non-Cancerous Non-Cancerous

Eyelid Cysts

Eccrine Cyst, Los Altos California

Eccrine Cyst

Eyelid Cancer or Non-Cancerous Non-Cancerous

Epithelial Inclusion Cyst  

Epithelial Inclusion Cyst

Eyelid Cancer or Non-Cancerous Non-Cancerous

Trichofolliculoma

Trichofolliculoma, Dr. Cockerham

Trichofolliculoma

Eyelid Cancer or Non-Cancerous Non-Cancerous

Apocrine Hidrocystomas

Apocrine Hidrocystomas

Apocrine Hidrocystomas

Eyelid Cancer or Non-Cancerous Non-Cancerous

Compound Nevus

Compound Nevus at Caleyes

Compound Nevus

Eyelid Cancer or Non-Cancerous Non-Cancerous

Intradermal Nevus

Intradermal Nevus

Intradermal Nevus

Eyelid Cancer or Non-Cancerous Non-Cancerous

Papilloma

Verruca Vulgaris Papilloma, Dr. Kimberly Cockerham

Verruca Vulgaris Papilloma

Eyelid Cancer or Non-Cancerous Non-Cancerous

Papilloma of the eye Los Altos California

Papilloma

Eyelid Cancer or Non-Cancerous Non-Cancerous

Seborrheic Keratosis

Seborrheic Keratosis

Seborrheic Keratosis

Eyelid Cancer or Non-Cancerous Non-Cancerous

This information is not meant to replace the advice of your physician and is not to be considered medical advice, diagnosis or treatment. Should you have any concern please contact your physician directly. Read our disclaimer

Skin Cancer: By the Numbers

  • Skin cancer is the most common form of cancer in the United States.1
  • Each year there are more new cases of skin cancer than the combined incidence of cancers of the breast, prostate, lung and colon.1
  • One in five Americans will develop skin cancer in the course of a lifetime. 2
  • Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) are the two major forms of non-melanoma skin cancer. 3
    • Between 40 and 50 percent of Americans who live to age 65 will have either skin cancer at least once.
    • BCC is the most common form of skin cancer; about one million of the cases diagnosed annually are basal cell carcinomas. 4 BCCs are rarely fatal, but can be highly disfiguring.
    • SCC is the second most common form of skin cancer. More than 250,000 cases are diagnosed each year1, resulting in approximately 2,500 deaths.2

Eyelid Oncology

Listen
Ask the right questions

Look
For warning signs

Feel
The region of interest

Eyelid oncology at Caleyes

Classic Risk Factors

  • Elderly caucasian
  • Light complexion/blue eyes
  • Actinic damage (sun damage)
  • Cigarette smoking
American Cancer Society. Cancer Facts & Figures 2009. Atlanta: American Cancer Society; 2009.
Robinson JK. Sun Exposure, Sun Protection, and Vitamin D. JAMA 2005; 294: 1541-43.
"Sun Protection." National Cancer Institute's Cancer Trends Progress Report - 2007 Update. 15 April 2008. Link.
"What is Squamous and Basal Cell Skin Cancer?" American Cancer Society. 5 May 2008. Link.

More than 90 % of Non-Melanoma Skin Cancer is Caused by Sun Exposure

  • Unprotected exposure
  • Outdoors even in the fog
  • Tanning booths
  • Through car, home or office windows
  • Yet only 33% of women and 10% of men wear daily sun block
  • Learn More: www.skincancer.org

Risk Factors Specific to Squamous Cell Carcinoma

  • HPV 16 and 18 (Human papilloma virus)
  • Immunosuppression (weakened immune system)
  • HIV – atypical, younger patients
  • Organ transplant
  • Xeroderma pigmentosum ( a genetic skin disorder)
  • Predisposition for epithelial tumors

Incidence Of Skin Cancers in the Young

Incidence:

  • Melanoma has tripled
  • Squamous cell carcinoma and basal cell carcinoma have doubled

1 in 5 Americans in their 20's and 30's will be diagnosed with skin cancer.
Men: are twice as likely as women to be diagnosed with skin cancer.

Skin Cancer Affects Non-Caucasians Too

Melanoma of the skin
Hispanic: birth to death risk
Male: .45 (1 in 221)
Female: .49 (1 in 205)

skin cancer bar graph

skin cancer bar graph

Skin Cancer MORE deadly for African Americans, Asians & Latinos

Caucasians

1974-1976: 81 %
1995-2001: 92 %

African Americans

1974-1976: 67%
1995-2001: 76%

Melanoma Surveillance, Epidemiology and End Results Program, 1975-2002, National Cancer Institute 2005; American Cancer Society, Surveillance Research, 2006

Melanoma graph

U.S. Skin Cancer Statistics

  • Incidence of has tripled since 1980
  • Early detection is crucial !

What to Look for

History: Have you had a prior skin cancer ?

  • If history of BCCA -> 50% have second lesion at 5 years
  • If history of SCCA -> 75% have second lesion at 5 years

Think beyond the face:

  • Women: lower legs
  • Men: back

Do you have:

  • Pain ? (Usually painless)
  • Intermittent scaling or scabbing?
  • Irritation when wearing glasses?

Waring Signs:

American Cancer Association’s ABCDE

A Asymmetry - draw a line down the center
B Border irregularity - Uneven, scalloped or notched
C Color variations - Brown, tan, black mixed with red, white or blue
D Diameter > Larger than a pencil’s eraser

American Cancer Society’s Look for warning signs ABCDE

Evolution = NEW ANYTHING

  • Grows or shrinks (suddenly)
  • Irritation, redness
  • Scaling
  • Crusting, oozing or bleeding
  • Tenderness or pain

Eyelid Specific Warning Signs

  • Telangiectasis (increase of small blood vessels)
  • Vessel blanching (whitening of the blood vessels)Loss of lashes
  • Trichiasis (misdirected eye lashes) Hyperpigmentation (increase of pigmentation) Hypopigmentation (decrease of pigmentation Sebaceous)

Cell Carcinoma The Worst Offender

  • Least common
  • 50% misdiagnosed
  • Average age: 72 years old
  • Women: Men = 2:1
  • Ectropion/entropion 10%
  • Caruncle 5% (inner corner of the eye)
  • Chronic conjunctivitis, cyst or pannus (red, inflamed eye)

Palpation is Important

  • Feel the region of interest
  • Firm
  • Irregular
  • Nodular
  • Check for lymph nodes
Sebaceous cell carcinoma Melanoma
Preauricular, (in front of ear) or cervical nodes 4%
Lung
Bone
Brain
Regional lymph nodes
Liver
Brain
Bone


Biopsy Options

  • Punch biopsy
  • Pentagonal wedge
  • Conjunctival mapping
  • Mohs
  • Skin Only – beware of what lies at the base of a cutaneous horn

SCCA Treatment

Surgical resection: 2-3 mm margins

Conclusion

ABCDE too simplistic Eyelids have their own special clues
Suspicious lesions MUST be biopsed If the answer doesn’t make sense; a second biopsy should be done.
Wear Sun block

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